Cancer, aging and cellular senescence.

Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy

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Normal cells do not divide indefinitely due to a process termed cellular or replicative senescence. Several lines of evidence suggest that replicative senescence evolved to protect higher eukaryotes, particularly mammals, from developing cancer. Senescent cells differ from Continue reading Cancer, aging and cellular senescence.

Senescent Cells

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA | PDF Source N.I.H.

Survey of senescent cell markers with age in human tissues

PDF Doc – Survey of senescent cell markers with age in human tissues

Telomeres: beacons of autocrine and paracrine DNA damage during skin aging.

Chronic inflammation induces telomere dysfunction and accelerates ageing… | PDF Doc – Chronic inflammation induces telomere dysfunction and accelerates ageing in mice

The Emerging Role of Senescence in Ocular Disease | PDF DocThe Emerging Role of Senescence in Ocular Disease

PDF | Targeting senescent cells in translational medicine Content Source[charts & diagrams]